Start-up overload: Main reason to PC slow down

Over time, as you add more and more programs to your computer, many of these applications automatically add themselves to your Windows Start-up folder. Additionally, these applications can add themselves quietly to a hidden area of your Windows Start-up system (accessed via the MSCONFIG run command). In extreme cases your PC will appear completely frozen.Limiting the number of applications loading themselves at start-up can speed boot times considerably and increase overall system performance.you can use some particular softwares for manage start-up for example "Regcure"(try it you can also make scan and repair the system errors by this software ). clean the start up and make your PC speed up.